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Amneal Pharma’s, 4,5-Dihydro-1H-pyrazolo[3,4-d]pyrimidine containing...
Share: Cas 1580464-40-9 MW458.97, C24 H19 Cl N6 S, 1H-Pyrazolo[3,4-d]pyrimidin-6-amine, 4-(4-chlorophenyl)-4,7-dihydro-3-methyl-1-(10H-phenothiazin-2-yl)-...
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Recilisib Sodium, EX-RAD
Share: Recilisib Sodium Phase I C16H12ClNaO4S Molecular Weight: 358.771849 g/mol A protein kinase inhibitor potentially for the treatment of acute radiation syndrome....
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Novartis, Torrent drug for diabetes, NVP-LBX192, LBX-192
Share: (R)-3-Cyclopentyl-N-(5-methoxy-thiazolo[5,4-b]pyridin-2-yl)-2-[4-(4-methyl-piperazine-1-sulfonyl)-phenyl]-propionamide...
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(±)-Integrifolin, Compound from plants keeps human cancer cells from multipying
Share: CAS 89647-87-0 MFC15 H18 O4, MW 262.30 Azuleno[4,5-b]furan-2(3H)-one, decahydro-4,8-dihydroxy-3,6,9-tris(methylene)-, (3aR,4R,6aR,8S,9aR,9bR)-...
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Mechanism of Action of the Cytotoxic Macrolides Amphidinolide X and J
Share: Acting on actin: The mechanism of action of amphidinolide X and amphidinolide J, two relatively small cytotoxic macrolides, has been elucidated. They do not target microtubules and intermediate...
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UCT Drug Discovery and Development Centre, H3D, pioneers world-class drug...
Share: UCT’s H3D is a center of excellence for research and innovation with an already strong track record in malaria drug discovery. The vision of H3D is to be the leading organization for...
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Racecadotril, acetorphan
Share: Racecadotril; CAS 81110-73-8; Acetorphan; Benzyl 2-(3-(acetylthio)-2-benzylpropanamido)acetate; Tiorfan; CADOTRIL; benzyl 2-[[2-(acetylsulfanylmethyl)-3-phenylpropanoyl]amino]acetate...
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Roxadustat, ASP 1517, FG 4592
Share: ROXADUSTAT ASP1517; ASP 1517; ASP-1517; FG-4592; FG 4592; FG4592; Roxadustat. CAS 808118-40-3 Chemical Formula: C19H16N2O5 Exact Mass: 352.10592 Fibrogen, Inc. THERAPEUTIC CLAIM, Treatment of...
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C–H Arylation of Heterocyclic N-Oxides Through in Situ Diazotisation Of...
Share: A green and selective method for the generation of biaryl compounds through C–H arylation of heterocyclic N-oxides, in which the addition of ascorbic acid as a promoter is not required for...
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Kinetics of Rh(II)-Catalyzed α-Diazo-β-ketoester Decomposition and...
Share: Kinetics of Rh(II)-Catalyzed α-Diazo-β-ketoester Decomposition and Application to the [3+6+3+6] Synthesis of Macrocycles on a Large Scale and at Low Catalyst Loadings Daniele Poggiali†,...
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Understanding the chemistry behind the antioxidant activities of butylated...
Share:Highlights Modification of BHT has a significant multivariate effect on antioxidant efficiency. BDE is the key to rational design and development of antioxidants. Antioxidant performance of BHT...
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Discovery and development of natural product oridonin-inspired anticancer agents
Share: Natural products have historically been, and continue to be, an invaluable source for the discovery of various therapeutic agents. Oridonin, a natural diterpenoid widely applied in traditional...
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Eldecalcitol, an active vitamin D3 analog used to treat osteoporosis
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Mastoparan
Share: Mastoparan, Peptide (H-INLKALAALAKKIL-NH2) IUPAC Condensed H-Ile-Asn-Leu-Lys-Ala-Leu-Ala-Ala-Leu-Ala-Lys-Lys-xiIle-Leu-NH2 LINUCS...
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Febuxostat
Share: Febuxostat Febuxostat; 144060-53-7; Uloric; Adenuric; Tei 6720; 2-(3-cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic acid; Molecular Formula: C16H16N2O3S Molecular Weight: 316.37484 g/mol...
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Besifloxacin hydrochloride (Besivance)
Share: Besifloxacin SS 734, BOL 303224A, ISV-403 MW 430.301, MF C19H21ClFN3O3 141388-76-3 CAS 7-[(3R)-3-aminoazepan-1-yl]-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid...
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Chemistry in Water
Share: Chemistry in Water 1 Isley et al. reported the use of the nonionic amphiphile TPGS-750-M (2 wt %) in water to facilitate nucleophilic aromatic substitution reactions (SNAr) with oxygen,...
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RG 6080
Share: RG-6080 Sulfuric acid, mono[(1R,2S,5R)-2-[[(2-aminoethoxy)amino]carbonyl]-7-oxo-1,6-diazabicyclo[3.2.1]oct-6-yl] ester Phase I A β-lactamase inhibitor potentially for the...
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Darolutamide
Share: Darolutamide N-((S)-1-(3-(3-Chloro-4-cyanophenyl)-1H-pyrazol-1-yl)-propan-2-yl)-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide N-((S)- 1 -(3-(3-chloro-4-cyanophenyl)- lH-pyrazol- 1...
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High Throughput Enzymatic Enantiomeric Excess: Quick-ee
Share:. High throughput screening techniques (HTS) are fast and efficient alternatives to evaluate enzymatic activities. Here, this technique is applied to obtain enantiomeric excess and conversions...
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