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MIRABEGRON
Share:MIRABEGRON Betanis Myrbetriq UNII-MVR3JL3B2V YM 178 YM178 Мирабегрон ميرابيغرون 米拉贝隆 2-(2-Amino-1,3-thiazol-4-yl)-N-[4-(2-{[(2R)-2-hydroxy-2-phenylethyl]amino}ethyl)phenyl]acetamide MF:...
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IVACAFTOR
Share: IVACAFTOR N-(2,4-di-tert-butyl-5-hydroxyphenyl)-l,4-dihydro-4- oxoquinoline-3-carboxamide N-(2,4-Di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide...
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Filgotinib
Share: Filgotinib C21H23N5O3S MW425.504 Elemental Analysis: C, 59.28; H, 5.45; N, 16.46; O, 11.28; S, 7.54 1206161-97-8 Cyclopropanecarboxamide,...
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FDA approves flibanserin first treatment for sexual desire disorder
Share: Flibanserin BIMT-17 BIMT-17-BS 1,3-Dihydro-1-(2-(4-(3-(trifluoromethyl)phenyl)-1-piperazinyl)ethyl)-2H-benzimidazol-2-one 167933-07-5 FDA approves first treatment for sexual desire disorder...
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Gamendazole a novel drug candidate for male contraception.
Share: Gamendazole (E) 3-(1-(2,4-Dichlorobenzyl)-6-(trifluoromethyl)-1H-indazol-3-yl)acrylic Acid trans-3-(1-Benzyl-6-(trifluoromethyl)-1H-indazol-3-yl)acrylic acid)...
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Lusutrombopag….Oral thrombopoietin (TPO) mimetic
Share: Lusutrombopag (E)-3-[2,6-dichloro-4-[[4-[3-[(1S)-1-hexoxyethyl]-2-methoxyphenyl]-1,3-thiazol-2-yl]carbamoyl]phenyl]-2-methylprop-2-enoic acid...
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Benzyl 3-deoxy-3-(3,4,5-trimethoxybenzylamino)-β-L-xylopyranoside
Share: The title compound was synthesized by opening the epoxide of benzyl 2,3-anhydro-β-L-ribopyranoside with 3,4,5-trimethoxybenzylamine (Scheme 1). The three broad peaks in the 1 H-NMR due to one...
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ASLAN Pharmaceuticals Gains Orphan Designation for Rare Cancer Drug ASLAN001...
Share: (R)-N4-[3-Chloro-4-(thiazol-2-ylmethoxy)-phenyl]-N6-(4-methyl-4,5-dihydro-oxazol-2-yl)-quinazoline-4,6-diamine ASLAN001 , Varlitinib C22H19ClN6O2S Molecular Weight: 466.94 Elemental...
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An introduction to the Prequalification of Active Pharmaceutical Ingredients
Share: An introduction to the Prequalification of Active Pharmaceutical Ingredients The WHO Prequalification of Medicines Programme (PQP) facilitates access to quality medicines through assessment...
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Chemical synthesis of IL-10 cytokine 90% cheaper than bioproduction, Provepep
Share:Chemical synthesis of IL-10 cytokine 90% cheaper than bioproduction, Provepep By Dan Stanton+, 08-Oct-2015 Chemical synthesis of peptides and proteins can be done at a tenth of the cost of...
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MAVATREP, JNJ 39439335,
Share: Mavatrep; UNII-F197218T99; Mavatrep (USAN); JNJ-39439335; 956274-94-5; 2-(2-(2-(2-(4-trifluoromethylphenyl)vinyl)-1H-benzimidazol-5-yl)phenyl)propan-2-ol...
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Tafluprost
Share: isopropyl (5Z)-7-{(1R,2R,3R,5S)-2-[(1E)-3,3-difluoro-4-phenoxybut-1-en-1-yl]-3,5-dihydroxycyclopentyl}hept-5-enoate, Tafluprost propan-2-yl...
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A monolith immobilised iridium Cp* catalyst for hydrogen transfer reactions...
Share: An immobilised monolithic iridium hydrogen transfer catalyst has been developed for use in flow based processing. The monolithic construc thas been used for several redox reductions...
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MONITORING FLUORINATIONS……Selective direct fluorination for the synthesis of...
Share: . Optimisation and real time reaction monitoring of the synthesis of 2-fluoromalonate esters by direct fluorination using fluorine gas is reported. An assessment of green metrics including atom...
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Facts, Growth, and Opportunities in Industrial Biotechnology
Share: The revolution in synthetic biology has enabled innovative manufacture of biofuels and the development of biological processes for the manufacture of bulk and fine chemicals. This short review...
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WO 2016018024, DAPAGLIFLOZIN, HANMI FINE CHEMICAL CO., LTD, New patent
Share: (S) – propylene glycol and water, 1: 1 crystalline complex PATENT WO2016018024, CRYSTALLINE COMPOSITE COMPRISING DAPAGLIFLOZIN AND METHOD FOR PREPARING SAME HANMI FINE CHEMICAL CO., LTD....
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BENFOTIAMINE
Share: Benfotiamine S-[(Z)-2-[(4-amino-2-methylpyrimidin-5-yl)methyl-formylamino]-5-phosphonooxypent-2-en-3-yl] benzenecarbothioate Benphothiamine; Betivina; Biotamin; Neurostop; Nitanevril;22457-89-2...
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ONL 1204 a small molecule peptide for Treatment of retinal detachment
Share: OR ONL 1204 CAS 1349038-53-4...
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AVORALSTAT
Share: Avoralstat, BCX4161, CAS 918407-35-9 UNII: UX17773O15 513.5513, C28-H27-N5-O5 2-Pyridinecarboxylic acid,...
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BRIVARACETAM
Share: BRIVARACETAM, UCB-34714 (2S)-2-[(4R)-2-oxo-4-propylpyrrolidin-1-yl]butanamide (2S)-2-[(4R)-2-Oxo-4-propyl-1-pyrrolidinyl]butanamide 1-Pyrrolidineacetamide, α-ethyl-2-oxo-4-propyl-, (αS,4R)- CAS...
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