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MK-7145

Share: MK-7145, cas  1255204-84-2 1(3H)-Isobenzofuranone, 5,5′-(1,4-piperazinediylbis((1R)-1-hydroxy-2,1-ethanediyl))bis(4-methyl- MF C26 H30 N2 O6, Molecular Weight 466.53 1(3H)​-​Isobenzofuranone,...

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MK 8718

Share: MK 8718 Cas 1582729-24-5 (free base); 1582732-29-3 (HCl). MF: C30H30ClF6N5O4 MW: 673.1891 INNOVATOR Merck Sharp & Dohme Corp., Merck Canada Inc....

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ICH M7

Share: ICH M7   Although relatively quiet in terms of any specific regulatory activities, the last 6 months have seen a plethora of publications that are associated with the ICH M7 guideline. Prominent...

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PDE4 inhibitor , Sumitomo Dainippon Pharma Company

Share:   2-[2-Methyl-1-(tetrahydro-2H-pyran-4-yl)-1H-benzimidazol-5-yl]-1,3-benzoxazole Hemifumarate Sumitomo Dainippon Pharma Company, CAS FREE FORM 1256966-65-0 Benzoxazole,...

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Chemical Engineering in China

Share:     Chemical Engineering in China Current trends of chemical engineering in the world’s biggest chemical market Read more...

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Quisapride Hydrochloride

Share: Quisapride Hydrochloride (R) – quinuclidine-3-5 – ((S) -2 – (( 4 – amino-5-chloro-2-ethoxy benzoylamino) methyl) morpholino) hexanoate IND Filed china A 5-HT4 agonist potentially for the...

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DSM 265 a promising Antimalarial

Share:  DSM265 DSM-265; PfSPZ 2-(1,1-difluoroethyl)-5-methyl-N-(4-(pentafluoro-l6-sulfanyl)phenyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine 2-(l,l-difluoroethyl)-5-methyl-N-[4-(pentafluoro- 6–...

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Chelation-Controlled Bergman Cyclization: Synthesis and Reactivity of...

Share: Chelation-Controlled Bergman Cyclization: Synthesis and Reactivity of Enediynyl Ligands ● Basak, Amit; Mandal, Subrata; Bag, Subhendu Sekhar● Chemical Reviews2003,  103(10),  4077-4094....

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Higenamine Hydrochloride

Share: Higenamine Hydrochloride 6,7-Isoquinolinediol, 1,2,3,4-tetrahydro-1-[(4-hydroxyphenyl)methyl]-, hydrochloride (9CI) 6,7-Isoquinolinediol, 1,2,3,4-tetrahydro-1-[(4-hydroxyphenyl)methyl]-,...

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FDA approved a switchover from batch to the new technology for production of...

Share: Above is an Illustration example,   FDA urges companies to get on board with continuous manufacturing The FDA gave Johnson & Johnson’s ($JNJ) Janssen drug unit the thumbs up last week for...

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Antimycobacterial Agents

Share: Styryl Hydrazine Thiazole Hybrids Will be updated………kindly email amcrasto@gmail.com DATA ABOUT Dehydrozingerone Dehydrozingerone; Feruloylmethane; 1080-12-2;...

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CFI-402257

Share:    CFI-402257 N-cyclopropyl-4-(7-((((1s,3s)-3-hydroxy-3-methylcyclobutyl)methyl)amino)-5-(pyridin-2-yloxy)pyrazolo[1,5-a]pyridin-3-yl)-2-methylbenzamide N-cyclopropyl-4-(7-( (((Is,...

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SETIPIPRANT

Share: Setipiprant, KYTH-105 CAS  866460-33-5 2-(2-(1-naphthoyl)-8-fluoro-1,2,3,4-tetrahydropyrido[4,3-b]indol-5-yl)acetic acid...

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Flow synthesis of Fluoxetine

Share: Scheme 1: Flow synthesis of fluoxetine (46). PIC CREDIT, The synthesis of active pharmaceutical ingredients (APIs) using continuous flow chemistry,  Marcus Baumann and Ian R. Baxendale,...

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FDA approves new diagnostic imaging agent FLUCICLOVINE F-18 to detect...

Share: FLUCICLOVINE F-18 Cyclobutanecarboxylic acid, 1-amino-3-(fluoro-18F)-, trans- [ Molecular FormulaC5H818FNO2 Average mass132.124 Da Axumin (fluciclovine F 18) fluciclovinum (18F) GE-148 NMK36...

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[F-18](2S,4S)-4-(3-Fluoropropyl)glutamine

Share: [F-18](2S,4S)-4-(3-Fluoropropyl)glutamine CAS 1196963-79-7 MF C8 H15 F N2 O3 Heptanoic acid, 2-​amino-​4-​(aminocarbonyl)​-​7-​(fluoro-​18F)​-​, (2S,​4S)​- [18F](2S,4S)-4-FPGln...

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[18F]AMG 580

Share:   [18F]AMG 580 CAS 1879904-74-1 MF C26 H24 F N5 O3 NOTE………CAS OF AMG 580 IS 1227067-71-1, WITHOUT 18F AMG 580...

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GSK 6853

Share:    GSK 6853 CAS  1910124-24-1 C22 H27 N5 O3, 409.48 Benzamide, N-​[2,​3-​dihydro-​1,​3-​dimethyl-​6-​[(2R)​-​2-​methyl-​1-​piperazinyl]​-​2-​oxo-​1H-​benzimidazol-​5-​yl]​-​2-​methoxy- (R)-N-(1...

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Targeted Nanoparticles for the Delivery of Novel Bioactive Molecules to...

Share: Pancreatic ductal adenocarcinoma (PDAC) is an aggressive disease with poor prognosis and limited therapeutic options. Therefore, there is an urgent need to identify new, safe, and targeted...

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CCT 245737

Share: CCT 245737 CAS:1489389-18-5 M.Wt: 379.34 Formula: C16H16F3N7O 2-​Pyrazinecarbonitrile​, 5-​[[4-​[[(2R)​-​2-​morpholinylmethyl]​amino]​-​5-​(trifluoromethyl)​-​2-​pyridinyl]​amino]​-...

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