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Share: MK-7145, cas 1255204-84-2 1(3H)-Isobenzofuranone, 5,5′-(1,4-piperazinediylbis((1R)-1-hydroxy-2,1-ethanediyl))bis(4-methyl- MF C26 H30 N2 O6, Molecular Weight 466.53 1(3H)-Isobenzofuranone,...
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Share: MK 8718 Cas 1582729-24-5 (free base); 1582732-29-3 (HCl). MF: C30H30ClF6N5O4 MW: 673.1891 INNOVATOR Merck Sharp & Dohme Corp., Merck Canada Inc....
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Share: ICH M7 Although relatively quiet in terms of any specific regulatory activities, the last 6 months have seen a plethora of publications that are associated with the ICH M7 guideline. Prominent...
View ArticlePDE4 inhibitor , Sumitomo Dainippon Pharma Company
Share: 2-[2-Methyl-1-(tetrahydro-2H-pyran-4-yl)-1H-benzimidazol-5-yl]-1,3-benzoxazole Hemifumarate Sumitomo Dainippon Pharma Company, CAS FREE FORM 1256966-65-0 Benzoxazole,...
View ArticleChemical Engineering in China
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Share: Quisapride Hydrochloride (R) – quinuclidine-3-5 – ((S) -2 – (( 4 – amino-5-chloro-2-ethoxy benzoylamino) methyl) morpholino) hexanoate IND Filed china A 5-HT4 agonist potentially for the...
View ArticleDSM 265 a promising Antimalarial
Share: DSM265 DSM-265; PfSPZ 2-(1,1-difluoroethyl)-5-methyl-N-(4-(pentafluoro-l6-sulfanyl)phenyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine 2-(l,l-difluoroethyl)-5-methyl-N-[4-(pentafluoro- 6–...
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Share: Chelation-Controlled Bergman Cyclization: Synthesis and Reactivity of Enediynyl Ligands ● Basak, Amit; Mandal, Subrata; Bag, Subhendu Sekhar● Chemical Reviews2003, 103(10), 4077-4094....
View ArticleHigenamine Hydrochloride
Share: Higenamine Hydrochloride 6,7-Isoquinolinediol, 1,2,3,4-tetrahydro-1-[(4-hydroxyphenyl)methyl]-, hydrochloride (9CI) 6,7-Isoquinolinediol, 1,2,3,4-tetrahydro-1-[(4-hydroxyphenyl)methyl]-,...
View ArticleFDA approved a switchover from batch to the new technology for production of...
Share: Above is an Illustration example, FDA urges companies to get on board with continuous manufacturing The FDA gave Johnson & Johnson’s ($JNJ) Janssen drug unit the thumbs up last week for...
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Share: Styryl Hydrazine Thiazole Hybrids Will be updated………kindly email amcrasto@gmail.com DATA ABOUT Dehydrozingerone Dehydrozingerone; Feruloylmethane; 1080-12-2;...
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View ArticleFlow synthesis of Fluoxetine
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View ArticleFDA approves new diagnostic imaging agent FLUCICLOVINE F-18 to detect...
Share: FLUCICLOVINE F-18 Cyclobutanecarboxylic acid, 1-amino-3-(fluoro-18F)-, trans- [ Molecular FormulaC5H818FNO2 Average mass132.124 Da Axumin (fluciclovine F 18) fluciclovinum (18F) GE-148 NMK36...
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View ArticleGSK 6853
Share: GSK 6853 CAS 1910124-24-1 C22 H27 N5 O3, 409.48 Benzamide, N-[2,3-dihydro-1,3-dimethyl-6-[(2R)-2-methyl-1-piperazinyl]-2-oxo-1H-benzimidazol-5-yl]-2-methoxy- (R)-N-(1...
View ArticleTargeted Nanoparticles for the Delivery of Novel Bioactive Molecules to...
Share: Pancreatic ductal adenocarcinoma (PDAC) is an aggressive disease with poor prognosis and limited therapeutic options. Therefore, there is an urgent need to identify new, safe, and targeted...
View ArticleCCT 245737
Share: CCT 245737 CAS:1489389-18-5 M.Wt: 379.34 Formula: C16H16F3N7O 2-Pyrazinecarbonitrile, 5-[[4-[[(2R)-2-morpholinylmethyl]amino]-5-(trifluoromethyl)-2-pyridinyl]amino]-...
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